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GSK2141795 CAS NO.1047634-65-0
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
- Payment Terms: L/C
- Available Specifications:
≥98.0%(100-500)Gram≥98.0%(1000-5000)Gram
- Product Details
Keywords
- GSK2141795
- GSK2141795;Uprosertib
- 1047634-65-0
Quick Details
- ProName: GSK2141795
- CasNo: 1047634-65-0
- Molecular Formula: C18H16Cl2F2N4O2
- Appearance: White crystal
- Application: CAS：1047634-65-0； GSK2141795;Uprosert...
- DeliveryTime: 3 months
- PackAge: 100g,500g,1kg,25kg/drum
- Port: shang hai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 98%
- Storage: Dry seal
- Transportation: shipping
- LimitNum: 100 Gram
Superiority
We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research.
We are committed to provide excellence in researching, manufacturing and drug discovery process.
Our research team of scientists consists of western-trained Ph.D.s with experience and capabilities in drug R&D methodologies and medicinal chemistry.
Details
GSK2141795 is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM for Akt1, 328 nM for Akt2, and 38 nM for Akt3 respectively (Clinical phase 1).
IC50 value: 180/328/38 nM (Akt1/2/3)
Target: pan-Akt inhibitor
KD values of 16 nM for Akt1, 49 nM for Akt2, and 5 nM for Akt3 (for GSK2141795), which are in line with literature data from biochemical assays that report potencies of 2 nM for Akt1, 2-13 nM for Akt2, and 3-9 nM Akt3 for GSK690693.