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Ezetimide，SCH-58235 CAS NO.163222-33-1
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
- Payment Terms: L/C
- Available Specifications:
≥98.0%(100-500)Gram≥98.0%(1000-5000)Gram
- Product Details
Keywords
- 163222-33-1
- Ezetimide，SCH-58235
- 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one EZETIMIBE ZETIA Ezitimibe&Int EzetimibeC24H21F2N03 (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3
Quick Details
- ProName: Ezetimide，SCH-58235
- CasNo: 163222-33-1
- Molecular Formula: C24H21F2NO3
- Appearance: White crystal
- Application: Pharmaceutical intermediates
- DeliveryTime: 4weeks
- PackAge: 100g,500g,1kg,25kg/drum
- Port: shang hai
- ProductionCapacity: 1000 Gram/Month
- Purity: ≥98.0%
- Storage: Dry seal
- Transportation: shipping
- LimitNum: 100 Gram
Superiority
98%
Details
Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added to statin treatment.
IC50 value:
Target: cholesterol-absorption
Ezetimibe is a lipid-lowering drug that inhibits the intestinal absorption of dietary and biliary cholesterol by blocking passage across the intestinal wall. In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant difference in changes in intima-media thickness, as compared with simvastatin alone, despite decreases in levels of LDL cholesterol and C-reactive protein. (ClinicalTrials.gov number, NCT00552097.) Ezetimibe offers a new therapeutic option for patients receiving statins who require further reduction in LDL cholesterol.