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CM 346(Obenoxazine), CAS NO.173352-21-1
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
- Payment Terms: L/C
- Available Specifications:
≥98.0%(100-500)Gram≥98.0%(1000-5000)Gram
- Product Details
Keywords
- CM 346(Obenoxazine),
- CM 346;Obenoxazine;Afobazole;CM 346(Obenoxazine);CM 346 4-(2-(5-ETHOXY-1H-BENZO[D]IMIDAZOL-2-YLTHIO)ETHYL)MORPHOLINE;Obenoxazine HCl;Obenoxazine hydrochloride
- 173352-21-1
Quick Details
- ProName: CM 346(Obenoxazine),
- CasNo: 173352-21-1
- Molecular Formula: C15H21N3O2S
- Appearance: White crystal
- Application: CAS：173352-21-1； Small molecule inhib...
- DeliveryTime: 2 months
- PackAge: 100g,500g,1kg,25kg/drum
- Port: shang hai
- ProductionCapacity: 1000 Gram/Week
- Purity: 98%
- Storage: Dry seal
- Transportation: shipping
- LimitNum: 100 Gram
Superiority
We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research.
We are committed to provide excellence in researching, manufacturing and drug discovery process.
Our research team of scientists consists of western-trained Ph.D.s with experience and capabilities in drug R&D methodologies and medicinal chemistry.
Details
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
IC50 value:
Target: anxiolytic agent
Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.