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CID-2011756 CAS NO.638156-11-3
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
- Payment Terms: L/C
- Available Specifications:
≥98.0%(100-500)Gram≥98.0%(1000-5000)Gram
- Product Details
Keywords
- CID-2011756
- CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide;CID 2011756;5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide;5-(3-Chlorophenyl)-N-[4-morpholin-4-ym
- 638156-11-3
Quick Details
- ProName: CID-2011756
- CasNo: 638156-11-3
- Molecular Formula: C22H21ClN2O3
- Appearance: light yellow solid
- Application: CAS：638156-11-3； CID-2011756,5-(3-chl...
- DeliveryTime: 3 months
- PackAge: 100g,500,1kg.....
- Port: shang hai
- ProductionCapacity: 1000 Gram/Month
- Purity: 98%
- Storage: Dry seal
- Transportation: shipping
- LimitNum: 100 Gram
Superiority
We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research.
We are committed to provide excellence in researching, manufacturing and drug discovery process.
Our research team of scientists consists of western-trained Ph.D.s with experience and capabilities in drug R&D methodologies and medicinal chemistry.
Details
CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.
IC50 Value: 10±0.7 uM (cellular inhibition of phospho-Ser916-PKD1 activity) [1]
Target: PKD
CID 2011756, has pan-PKD inhibitory effects (PKD2 IC50 = 0.6±0.1 uM; PKD3 IC50 = 0.7±0.2 uM) with similar, albeit not identical, potencies which may be expected for an ATP competitive inhibitor. CID 2011756 was the most potent of the inhibitors with a cellular EC50 of 10±0.7 uM (n = 3), an EC50 value comparable to that of our previously described benzoxoloazepinolone.